molecular beacons

Molecular Beacon Patents and Patent Applications

You can download the Patents and Patent Applications pdf-document to view a complete list of countries in which patent applications are filed and to view a complete list of countries in which patents are issued, including their issue and termination dates.

 

    Patent and Patent Applications

  1. Hybridization Probes for Nucleic Acid Detection, Universal Stems, Methods and Kits
    (Filed in Australia, Canada, Europe and Japan)

    Download European patent EP0728218

  2. Detectably Labeled Dual Conformation Oligonucleotide Probes, Assays and Kits
    (Filed in Australia, Canada, Europe, Japan and the United States)

    Download US patent US05925517

    Download US patent US06103476

    Download European patent EP0745690

  3. Nucleic Acid Detection Probes Having Non-FRET Fluorescence Quenching
    and Kits and Assays Including Such Probes

    (Filed in Australia, Canada, Europe, Japan and the United States)

    Download US patent US06150097

    Download European patent EP0892808

  4. Non-Competitive Co-Amplification Methods
    (Filed in Australia, Canada, Japan and the United States)

    Download US patent US06461817

  5. Wavelength-Shifting Probes and Primers and Their Use in Assays and Kits
    (Filed in Australia, Canada, Europe, Japan and the United States)

    Download US patent US06037130

    Download European patent EP1100971

  6. Assays for Short Sequence Variants
    (Filed in Australia, Canada, Europe, Japan and the United States)

    Download US patent US7662550

    Download European patent EP1230387

  7. Homogenous Multiplex Screening Assays and Kits
    (Filed in Australia, Canada, China, Europe, Japan and the United States)

    Download US patent US07385043


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Recent Publications from our group


Catrina IE, Bayer LV, Yanez G, McLaughlin JM, Malaczek K, Bagaeva E, Marras SAE, and Bratu DP (2016) The temporally controlled expression of Drongo, the fruit fly homolog of AGFG1, is achieved in female germline cells via P-bodies and its localization requires functional Rab11. RNA Biol 13: 1117-1132.



Vargas DY, Kramer FR, Tyagi S, and Marras SAE. (2016) Multiplex real-time PCR assays that measure the abundance of extremely rare mutations associated with cancer. PLoS ONE 11, e0156546.


We describe the use of “SuperSelective” primers that enable the detection and quantitation of somatic mutations whose presence relates to cancer diagnosis, prognosis, and therapy, in real-time multiplex PCR assays that can potentially analyze rare DNA fragments present in blood samples (liquid biopsies), thereby providing information that can be used to modify therapy for individual patients, prolonging (and improving the quality of) life.

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